Unseen Upside: Investments Beyond Their Returns

Cambridge Associates

How we invest today drives tomorrow’s innovations. Through conversations with investors and entrepreneurs, explore how investment decisions have the potential to improve our lives in unexpected ways. Powered by the network of Cambridge Associates, host Hillary Ribaudo explores the investments being made that will redefine our future. Join us to uncover the Unseen Upside.

2025 Unseen Upside

How we invest today drives tomorrow’s innovations. Through conversations with investors and entrepreneurs, explore how investment decisions have the potential to improve our lives in unexpected ways. Powered by the network of Cambridge Associates, host Hillary Ribaudo explores the investments being made that will redefine our future. Join us to uncover the Unseen Upside.

2025 Unseen Upside

17hr 20min

Thumbnail for "S5:E7 Mini Episode | What Inspires Our Guests: Must-Read Books and Podcasts, Pt 2".

A podcast about investments beyond their returns

August 27, 20255min 20sec7.67 MB

Thumbnail for "S6:EP0 Unseen Upside - Season 6 Trailer".

A podcast about investments beyond their returns - returning October 21

October 14, 20253min 43sec7.14 MB

Thumbnail for "S5:E8 Mini Episode | The Story of Saving the American Bison".

A podcast about investments beyond their returns

October 3, 20259min 58sec14.34 MB

Thumbnail for "S5:E6 Mini Episode | What Inspires Our Guests: Must-Read Books and Podcasts, Pt 1".

A podcast about investments beyond their returns

June 27, 20256min 28sec9.3 MB

Thumbnail for "S5:E5 The Maternal Health Crisis: Investing for Change".

A podcast about investments beyond their returns

December 3, 202445min 45sec87.85 MB

Thumbnail for "S5:E4 Digital Health: Transforming Care, Improving Access".

A podcast about investments beyond their returns

November 19, 202437min 36sec72.2 MB

Thumbnail for "S5:E3 From Barriers to Bridges: Rural Health Access".

A podcast about investments beyond their returns

November 5, 202440min 33sec77.87 MB

Thumbnail for "S5:E2 Drug Affordability: The High Cost of Healing".

A podcast about investments beyond their returns

October 22, 202443min 8sec82.84 MB

Thumbnail for "S5:E1 Investing in Affordable Homes for Healthier Communities".

A podcast about investments beyond their returns

October 8, 202433min 53sec65.06 MB

Thumbnail for "S5:EP0 Unseen Upside - Season Five Trailer".

A podcast about investments beyond their returns - coming October 8

October 1, 20243min 1sec5.8 MB

Thumbnail for "The Decision to Delegate".

August 14, 202434min 2sec48.95 MB

Thumbnail for "S4:E6 AI & Healthcare: The Next Frontier".

April 16, 202446min 51sec89.97 MB

Thumbnail for "S4:E5 Unlocking the Dark Genome for Lupus and Other Autoimmune Diseases".

Decoding the once mysterious "dark genome" could bring new therapies for those suffering from Lupus.

April 2, 202443min 51sec84.12 MB

Thumbnail for "S4:EP4 Appetite for Change: The Obesity Epidemic Meets Biotech ".

Discover more about the investment landscape and future of obesity therapeutics, focusing on GLP-1 drugs like Ozempic that curb appetite.

March 19, 202443min 53sec84.19 MB

Thumbnail for "S4:EP3 Precision Oncology & Advancing Personalized Cancer Care".

Join us as we investigate the promise of precision medicine to make cancer treatment more effective and more equitable

March 5, 202439min 3sec74.91 MB

Thumbnail for "S4:EP2 Living Longer But Losing Our Minds: The Alzheimer's Emergency".

This episode explores emerging therapeutics offering hope against neurodegenerative diseases.

February 20, 202440min 50sec78.33 MB

Thumbnail for "S4:EP1 Mind Matters: Making Sense of the Mental Health Crisis".

The mental health crisis is growing, especially among Gen Z (91% report anxiety or depression). Find out what industry leaders and investors are doing about it.

February 6, 202430min 27sec58.4 MB

Thumbnail for "S4:EP0 Unseen Upside - Season Four Trailer".

A show about investments beyond their returns - coming February 6

January 30, 20243min 27sec6.64 MB

Thumbnail for "S3:EP5 Can Deep Tech Combat Fast Fashion?".

The fashion industry accounts for up to 10% of global carbon dioxide output—and fast fashion is making things worse. But what if deep tech could help?

May 30, 202335min 46sec68.68 MB

Thumbnail for "S3:EP4 Battery Storage, Renewable Energy & Building a Sustainable Grid".

One company has developed an iron-air battery capable of storing energy for multiple days, which may be the missing link needed to decarbonize our grid.

May 16, 202337min 30sec72 MB

Thumbnail for "S3:EP3 eVTOLs & Flying Cars".

Humans have fantasized about flying cars for decades, but they’ve yet to leave the pages of our sci-fi books...or have they?

April 27, 202330min 59sec59.49 MB

Thumbnail for "S3:EP2 CRISPR, Dodo Birds, Woolly Mammoths & Gene Editing".

Dodo birds, woolly mammoths, and gene editing—oh my! Hear from Colossal Biosciences about their efforts to de-extinct the woolly mammoth and dodo bird to aid conservation and fight climate change.

April 11, 202339min 10sec75.23 MB

Thumbnail for "S3:EP1 Will Fusion Power (or "Stars in a Jar") Replace Fossil Fuels?".

Described as a star in a bottle, fusion is what powers our sun and stars but here on earth, it has always presented innumerable engineering challenges —until now.

March 28, 202332min 22sec62.16 MB

Thumbnail for "S3:EP0 Unseen Upside - Season Three Trailer".

A show about investments beyond their returns - coming March 28!

March 20, 20232min 10sec4.16 MB

Thumbnail for "S2:EP5 Space: Zero Gravity Space Factories".

For those of us without a seat on the next rocket, how will space innovation improve our lives here on Earth?

June 14, 202240min 57sec98.32 MB

Thumbnail for "S2:EP4 Water: Carbon Sinking Kelp Farms".

Investors are putting capital to work in ocean-based businesses to mitigate climate change and enhance the Blue Economy—but how?

June 2, 202240min 16sec96.68 MB

Thumbnail for "S2:EP3 Fire: Net-Zero Plasma Diamonds".

Fire is often a marker associated with the worst effects of climate change. But what if fire could actually be harnessed to help reverse it?

May 17, 202238min 48sec93.12 MB

Thumbnail for "S2:EP2 Air: Planting 20M Trees by 2030".

Carbon credit markets and the race to plant more trees

May 3, 202239min 4sec93.76 MB

Thumbnail for "S2:EP1 Earth: Mushrooms and the Future of Meat".

Alternative proteins and the future of nutritional ecosystems

April 19, 202236min 21sec87.25 MB

Thumbnail for "S2:EP0 Unseen Upside - Season Two Trailer".

A show about investments beyond their returns - coming April 19!

April 11, 20222min 47sec4.03 MB

Thumbnail for "S1:EP5 Consumer Brands: Why Do We Buy?".

Learn how technology and evolving consumer preferences are impacting how brands market themselves

November 16, 202123min 11sec44.52 MB

Thumbnail for "S1:EP4 Digital Health: How Is Tech Revolutionizing Healthcare?".

We've spent more time over the last 18+ months thinking about our health than ever before, but what will our healthcare system look like in the future?

November 2, 202134min 10sec65.6 MB

Thumbnail for "S1:EP3 Crypto: How Are Artists Leveraging NFTs?".

Learn about NFTs and the economic freedom they're providing artists

October 20, 202130min 56sec59.4 MB

Thumbnail for "S1:EP2 Digital Infrastructure: Where Does the Internet Come From?".

Explore digital infrastructure, the investments being made in fiber optic cables, and what that means for our daily lives.

September 28, 202123min 48sec45.71 MB

Thumbnail for "S1:EP1 Impact Investing: How Is Tech Making Food Systems More Sustainable?".

Explore impact investing through the lens of precision agriculture and sustainable farming

September 14, 202138min 1sec73 MB

Thumbnail for "S1:EP0 Introducing Unseen Upside".

A show about investments beyond their returns - coming September 14!

August 30, 20211min 55sec3.71 MB

S5:E7 Mini Episode | What Inspires Our Guests: Must-Read Books and Podcasts, Pt 2

Thumbnail for "S5:E7 Mini Episode | What Inspires Our Guests: Must-Read Books and Podcasts, Pt 2".

August 27, 20255min 20sec

Summer isn't over just yet--Unseen Upside is bringing you Part 2 of our summer reading list!

Tune in as we share more book recommendations from investors and entrepreneurs on the leading edge of healthcare.

Check the show notes for links to all the recommendations, and catch up on past episodes in our podcast feed. Stay tuned for Season 6—launching soon.

Featured Recommendations:

Guests Include:

Theresa Hajer, Head of US Venture Capital Research at Cambridge Associates
Alyssa Jaffe, Partner at Seven Wire Ventures
Lucas Trout, Lecturer on Global Health and Social Medicine at Harvard Medical School

Unseen Upside: Investments Beyond Their Returns is developed in partnership with PRX, an award-winning podcast media company.

Cambridge Associates is a global investment firm that works with endowments, foundations, healthcare systems, pension plans, and private clients to implement and manage custom investment portfolios that aim to generate outperformance and maximize their impact on the world. Cambridge Associates delivers a range of portfolio management services, including outsourced CIO, non-discretionary portfolio management, staff extension, and asset class mandates.