Psychedelics are now at the center of a global conversation about mental health, mysticism, and even how we experience illness and death. In Altered States, host Arielle Duhaime-Ross explores how people are taking these drugs, who has access to them, how they're regulated, who stands to profit, and what these substances might offer us as individuals and as a society.

In recent years, an increasing number of international clinics have begun offering treatments using ibogaine, a psychedelic drug that comes from a West African plant, to help treat conditions such as trauma and addiction. Much of the global supply of ibogaine is smuggled illegally out of Gabon. A former NBA basketball player from Gabon named Stéphane Lasme is at the forefront of new efforts to build a sustainable fair trade iboga industry.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-fair-trade-ibogaine/">link.</a>

In recent years, an increasing number of international clinics have begun offering treatments using ibogaine, a psychedelic drug that comes from a West African plant, to help treat conditions such as trauma and addiction. Much of the global supply of ibogaine is smuggled illegally out of Gabon. A former NBA basketball player from Gabon named Stéphane Lasme is at the forefront of new efforts to build a sustainable fair trade iboga industry.
For a transcript of this episode, please visit this link.

The story of one man’s journey from the jungles of Gabon to the NBA to the business of ibogaine.

Fair Trade Ibogaine 

The Noke Koi are an Indigenous group from Acre, Brazil who consider themselves guardians of the psychoactive plant brew ayahuasca, which they call “uni.” This summer, they traveled to the U.S. to spread an urgent message: their home in the Amazon is being destroyed.

The Noke Koi are an Indigenous group from Acre, Brazil who consider themselves guardians of the psychoactive plant brew ayahuasca, which they call “uni.” This summer, they traveled to the U.S. to spread an urgent message: their home in the Amazon is being destroyed.

On the road with Indigenous leaders from the Amazon

An Ayahuasca Message

When a neurosurgeon claimed he glimpsed the afterlife during a coma, skeptics offered a more earthly interpretation – a surge of DMT produced by his own body. Was his tale of eternity a trick of the brain, or a window into something science can’t explain?

When a neurosurgeon claimed he glimpsed the afterlife during a coma, skeptics offered a more earthly interpretation – a surge of DMT produced by his own body. Was his tale of eternity a trick of the brain, or a window into something science can’t explain?

An investigation into near-death experiences

Was it DMT? Or was it heaven?

Vivaldi. Bach. The Beatles. The Johns Hopkins playlist has been the standard soundtrack in psychedelic trials at Johns Hopkins and therapy rooms around the world for more than 25 years. It also skews toward Classical and Christian music. When Sughra Ahmed, a Muslim, enrolled in a psilocybin study that used this playlist, she didn’t love what she heard. So where did this playlist come from exactly? And what can science tell us about what role music plays in a trip?

Vivaldi. Bach. The Beatles. The Johns Hopkins playlist has been the standard soundtrack in psychedelic trials at Johns Hopkins and therapy rooms around the world for more than 25 years. It also skews toward Classical and Christian music. When Sughra Ahmed, a Muslim, enrolled in a psilocybin study that used this playlist, she didn’t love what she heard. So where did this playlist come from exactly? And what can science tell us about what role music plays in a trip?

What music should accompany a trip?

The Psychedelic Playlist

Nearly a decade ago, researchers at Johns Hopkins University gave some two dozen religious leaders from various faith backgrounds a high dose of psilocybin. Now, the long-awaited results of the study are out. Journalist Michael Pollan, who wrote about the research for The New Yorker, weighs in on whether science can ever truly measure mysticism.

Nearly a decade ago, researchers at Johns Hopkins University gave some two dozen religious leaders from various faith backgrounds a high dose of psilocybin. Now, the long-awaited results of the study are out. Journalist Michael Pollan, who wrote about the research for The New Yorker, weighs in on whether science can ever truly measure mysticism.

What happens when religious clergy take magic mushrooms?

A Priest, a Rabbi, and a Muslim Leader Get High

Over the next ten episodes we’re going to explore two distinct camps in the world of psychedelics. On one side there’s the realm of spiritualists, mystical experiences, and psychedelic churches. And on the other are scientists, clinical trials, animal studies and psychopharmacologists. These two camps are often far apart but when they get all tangled up together things get really interesting.

Over the next ten episodes we’re going to explore two distinct camps in the world of psychedelics. On one side there’s the realm of spiritualists, mystical experiences, and psychedelic churches. And on the other are scientists, clinical trials, animal studies and psychopharmacologists. These two camps are often far apart but when they get all tangled up together things get really interesting.

Psychedelic science, religion, and everything in between.

Coming Soon: Altered States Season 2

A former Navy SEAL named Craig deployed nine times over nearly three decades in the military. When he left the service, he felt lucky to have all his limbs, toes and fingers. But he found himself struggling with language and memory and rising frustration. One day he forgot his wife’s name and couldn’t remember it for hours. His wife Gretchen started looking for help online and found information about a Stanford University research study on ibogaine and veterans. Craig volunteered. For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-navy-seal-ibogaine/">link.</a>

A former Navy SEAL named Craig deployed nine times over nearly three decades in the military. When he left the service, he felt lucky to have all his limbs, toes and fingers. But he found himself struggling with language and memory and rising frustration. One day he forgot his wife’s name and couldn’t remember it for hours. His wife Gretchen started looking for help online and found information about a Stanford University research study on ibogaine and veterans. Craig volunteered. 
For a transcript of this episode, please visit this link.

A story of traumatic brain injury and a 24-hour trip.

A Navy SEAL Goes to Mexico to take Ibogaine

A plan to protect the peyote cactus is taking shape on the Winnebago Reservation in Nebraska during this summer’s Native American Church of North America conference. Indigenous leaders are hustling to take their peyote proposal all the way to the White House before the November election. Producer Adreanna Rodriguez tells the story.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-peyote-plan/">link.</a>

A plan to protect the peyote cactus is taking shape on the Winnebago Reservation in Nebraska during this summer’s Native American Church of North America conference. Indigenous leaders are hustling to take their peyote proposal all the way to the White House before the November election. Producer Adreanna Rodriguez tells the story.
For a transcript of this episode, please visit this link.

A big saga, a small cactus.

The Peyote Plan

When journalist Anna Silman started reporting on ketamine five years ago she did so because people in her friend group had begun taking the drug recreationally. She was intrigued by the ways that interest in psychedelic-assisted therapy meant more people were taking ketamine, both with a prescription and without one too. But as she started to see friends struggle with dependency, something other countries have been ringing the alarm about for years, she began to wonder whether the U.S. has been too naive. We hear from a woman we’re calling Olivia, just a few months out of rehab, who thinks the risks of ketamine have been severely underestimated.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-ketamine/">link.</a>

When journalist Anna Silman started reporting on ketamine five years ago she did so because people in her friend group had begun taking the drug recreationally. She was intrigued by the ways that interest in psychedelic-assisted therapy meant more people were taking ketamine, both with a prescription and without one too. But as she started to see friends struggle with dependency, something other countries have been ringing the alarm about for years, she began to wonder whether the U.S. has been too naive. We hear from a woman we’re calling Olivia, just a few months out of rehab, who thinks the risks of ketamine have been severely underestimated.
For a transcript of this episode, please visit this link.

A cautionary tale of k-holes, pharmaceuticals, party drugs and friends

 What if Ketamine is More Addictive Than We Thought?

At first the effort in Oregon to legalize psilocybin seemed doomed. Then the organizers started talking to the architect behind the carefully coordinated, state-by-state campaign to legalize cannabis, an attorney by the name of Graham Boyd. His initial thought was that what worked for cannabis would never work for psychedelics. But what he found in Oregon changed his mind. Producer Damiano Marchetti investigates.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-psychedelics-ballot/">link.</a>

At first the effort in Oregon to legalize psilocybin seemed doomed. Then the organizers started talking to the architect behind the carefully coordinated, state-by-state campaign to legalize cannabis, an attorney by the name of Graham Boyd. His initial thought was that what worked for cannabis would never work for psychedelics. But what he found in Oregon changed his mind. Producer Damiano Marchetti investigates.
For a transcript of this episode, please visit this link.

Will voters pass state ballot measures to legalize psychedelics like they did for cannabis?

Psychedelics on the Ballot

Ernesto Londoño is a national correspondent and former war correspondent at The New York Times. For most of his life, Ernesto was a classic journalist – skeptical, stoic – whose early life in war-torn Colombia and reporting experiences in Iraq and Afghanistan left him traumatized, though he didn’t know it. Then Ernesto signs up for a retreat in the Amazon where he drinks ayahuasca. This retreat is followed by many more throughout Latin America. These experiences began to melt some of his armor, revealing a surprising new side of himself. Along the way, Ernesto reports on the strange world of international psychedelics retreats.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-war-correspondent/">link.</a>

Ernesto Londoño is a national correspondent and former war correspondent at The New York Times. For most of his life, Ernesto was a classic journalist – skeptical, stoic – whose early life in war-torn Colombia and reporting experiences in Iraq and Afghanistan left him traumatized, though he didn’t know it. Then Ernesto signs up for a retreat in the Amazon where he drinks ayahuasca. This retreat is followed by many more throughout Latin America. These experiences began to melt some of his armor, revealing a surprising new side of himself. Along the way, Ernesto reports on the strange world of international psychedelics retreats.
For a transcript of this episode, please visit this link.

What happens when a New York Times reporter takes ayahuasca in the Amazon?

A Former War Correspondent Unravels

Altered States is taking a short breather and will be back soon. In the meantime, consider joining host Arielle Duhaime-Ross and other journalists for a virtual panel called <a href="https://psychedelics.berkeley.edu/event/the-new-psychedelic-beat-unraveling-oregons-drug-policy-story/">The New Psychedelic Beat: Unraveling Oregon’s Drug Policy Story</a> hosted by the UC Berkeley Graduate School of Journalism and the UC Berkeley Center for the Science of Psychedelics. September 25, 2024 at 1 pm PT.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/show-update/#more-55628">link.</a>

Altered States is taking a short breather and will be back soon. In the meantime, consider joining host Arielle Duhaime-Ross and other journalists for a virtual panel called The New Psychedelic Beat: Unraveling Oregon’s Drug Policy Story hosted by the UC Berkeley Graduate School of Journalism and the UC Berkeley Center for the Science of Psychedelics. September 25, 2024 at 1 pm PT.
For a transcript of this episode, please visit this link.

Show Update

Several years ago, Heather was given three doses of psilocybin as part of a clinical study for treatment-resistant depression. Ever since, she’s been experiencing strange visual distortions, including “visual snow” and shimmering walls. What’s it like to develop a chronic condition following a trip? And what do scientists know about why it happens and who’s at risk?For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-the-longest-trip/">link.</a>

Several years ago, Heather was given three doses of psilocybin as part of a clinical study for treatment-resistant depression. Ever since, she’s been experiencing strange visual distortions, including “visual snow” and shimmering walls. What’s it like to develop a chronic condition following a trip? And what do scientists know about why it happens and who’s at risk?
For a transcript of this episode, please visit this link.

What happens when the effects of a psychedelic experience won’t fully go away?

The Longest Trip

For the last couple of years, producer Shaina Shealy has been following Israeli and Palestinian peace activists who have been coming together to drink the psychedelic brew ayahuasca in an effort to heal their collective intergenerational trauma. It seemed to be helping them when suddenly the region erupts into chaos and violence.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-peace-seekers/">link.</a>

For the last couple of years, producer Shaina Shealy has been following Israeli and Palestinian peace activists who have been coming together to drink the psychedelic brew ayahuasca in an effort to heal their collective intergenerational trauma. It seemed to be helping them when suddenly the region erupts into chaos and violence.
For a transcript of this episode, please visit this link.

A story of intergenerational trauma and a psychedelic brew

The Peace Seekers

The U.S. Food and Drug Administration’s decision on MDMA-assisted therapy for post traumatic stress disorder.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-stat-fda-update/">link.</a>

The U.S. Food and Drug Administration’s decision on MDMA-assisted therapy for post traumatic stress disorder.
For a transcript of this episode, please visit this link.

Big news in the world of psychedelics

An FDA Update

The U.S. Food and Drug Administration is poised to decide whether to approve MDMA-assisted therapy for the treatment of post traumatic stress disorder. Host Arielle Duhaime-Ross interviews Michael Pollan, author of the best-selling book "How to Change Your Mind,” about how we got here, and what the decision might mean for the future of psychedelics.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-will-doctors-soon-prescribe-ecstasy/">link.</a>

The U.S. Food and Drug Administration is poised to decide whether to approve MDMA-assisted therapy for the treatment of post traumatic stress disorder. Host Arielle Duhaime-Ross interviews Michael Pollan, author of the best-selling book "How to Change Your Mind,” about how we got here, and what the decision might mean for the future of psychedelics.
For a transcript of this episode, please visit this link.

Can a psychedelic drug be a medicine? The federal government will soon decide.

Will Doctors Soon Prescribe Ecstasy?

In 2020, voters in Oregon passed a ballot measure that allows people to take magic mushrooms, or psilocybin, with a guide. But what does that actually look like — or sound like? Host Arielle Duhaime-Ross follows along with a licensed psilocybin facilitator as she guides a 67-year-old man on his first mushroom trip.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/altered-states-the-oregon-experiment/#more-50816">link.</a>

In 2020, voters in Oregon passed a ballot measure that allows people to take magic mushrooms, or psilocybin, with a guide. But what does that actually look like — or sound like? Host Arielle Duhaime-Ross follows along with a licensed psilocybin facilitator as she guides a 67-year-old man on his first mushroom trip.
For a transcript of this episode, please visit this link.

A report from the first state in the country to allow people to take mushrooms legally.

The Oregon Experiment

Psychedelics now inhabit a strange liminal space. Are they party drugs? Medications? Religious sacraments? In Altered States, host Arielle Duhaime-Ross explores how people are taking these drugs, who stands to profit, and what these substances might offer us as individuals and as a society.For a transcript of this episode, please visit this <a href="https://psychedelics.berkeley.edu/coming-soon-altered-states/#more-55621">link.</a>

Psychedelics now inhabit a strange liminal space. Are they party drugs? Medications? Religious sacraments? In Altered States, host Arielle Duhaime-Ross explores how people are taking these drugs, who stands to profit, and what these substances might offer us as individuals and as a society.
For a transcript of this episode, please visit this link.